NMR Restraints Grid
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NMR Restraints Grid |
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Result table
| image | mrblock_id | pdb_id | bmrb_id | cing | stage | position | program | type | subtype | subsubtype |
|
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11915 |
1s8k   |
6109 | cing | 1-original | 1 | DYANA/DIANA | distance | NOE | simple |
1 PCA
HA 1 PCA HB3 4.00 # 2 882100.0 e 4122-12 240
HA 2 THR HN 3.30 # 2 2883000.0 e 4122-12 426
2 THR
HN 2 THR HA 4.60 # 2 362400.0 e 4122-12 75
HN 2 THR HB 4.50 # 2 419400.0 e 4122-12 74
HN 3 GLN HN 3.90 # 2 985800.0 e 4122-12 186
HA 2 THR QG2 3.50 # s 1M 2155000.0 e 4122-12 243
HA 3 GLN HN 3.20 # 2 3299000.0 e 4122-12 44
HA 4 CYSS HN 4.60 # 3 264500.0 e 4122-12 375
HB 3 GLN HN 4.30 # 2 513700.0 e 4122-12 42
HB 4 CYSS HN 3.10 # 3 2991000.0 e 4122-12 377
QG2 4 CYSS HN 5.10 # 5M 427700.0 e 4122-12 128
3 GLN
HN 3 GLN HA 3.50 # 2 1827000.0 e 4122-12 447
HN 3 GLN HB2 3.00 <# 2 4487000.0 e 4122-12 36
HN 3 GLN HB3 3.80 ># 2 1176000.0 e 4122-12 464
HN 3 GLN HG2 4.80 ># 1 64760.0 e 4122-12 462
HN 3 GLN HG3 2.80 <# 1 1866000.0 e 4122-12 456
HN 4 CYSS HN 2.80 # 2 6759000.0 e 4122-12 203
HA 3 GLN HB2 3.50 # 2 1777000.0 e 4122-12 245
HA 3 GLN HB3 3.20 # 2 3456000.0 e 4122-12 244
HA 3 GLN HG2 2.90 <# 1 1306000.0 e 4122-12 246
HA 3 GLN HG3 3.70 ># 1 312400.0 e 4122-12 247
HA 4 CYSS HN 3.60 # 2 1673000.0 e 4122-12 134
HB2 3 GLN HG3 2.50 # s 1 3194000.0 e 4122-12 332
HB2 4 CYSS HN 3.80 <# 2 1182000.0 e 4122-12 130
HB2 24 THR HA 3.30 # 5 1217000.0 e 4122-12 233
HB2 25 CYSS HN 3.30 # 5 1124000.0 e 4122-12 59
HB3 4 CYSS HN 4.80 ># 2 284100.0 e 4122-12 129
HG2 3 GLN HE21 3.50 # 1 413200.0 e 4122-12 353
HG2 3 GLN HE22 2.90 # 1 1352000.0 e 4122-12 161
HG3 3 GLN HE21 3.80 # 1 280200.0 e 4122-12 164
HG3 3 GLN HE22 3.10 # 1 996700.0 e 4122-12 162
4 CYSS
HN 4 CYSS HB2 5.00 ># w 2 168100.0 e 4122-12 132
HN 4 CYSS HB3 3.80 <# 2 1160000.0 e 4122-12 388
HA 4 CYSS HB2 3.80 # 2 1178000.0 e 4122-12 220
HA 4 CYSS HB3 3.50 # 2 1786000.0 e 4122-12 217
HA 9 ASP HB2 3.40 # 5 945900.0 e 4122-12 218
HA 9 ASP HB3 3.20 # 5 1509000.0 e 4122-12 219
HB2 5 GLN HN 3.20 <# 2 3381000.0 e 4122-12 488
HB2 6 SER HN 3.00 <# 3 3484000.0 e 4122-12 431
HB2 9 ASP HN 4.10 # 5 306400.0 e 4122-12 122
HB2 9 ASP HB2 2.50 # s 5 10320000.0 e 4122-12 538
HB2 9 ASP HB3 2.60 # 5 4806000.0 e 4122-12 537
HB2 20 CYSS HB2 3.20 # 5 1322000.0 e 4122-12 525
HB2 20 CYSS HB3 4.30 # 5 252200.0 e 4122-12 291
HB3 5 GLN HN 3.80 ># 2 1188000.0 e 4122-12 491
HB3 6 SER HN 4.10 ># 3 530500.0 e 4122-12 433
HB3 9 ASP HB3 2.80 # 5 3416000.0 e 4122-12 295
5 GLN
HN 5 GLN HB2 3.10 <# 2 3702000.0 e 4122-12 493
HN 5 GLN HB3 3.80 ># 2 1109000.0 e 4122-12 492
HN 6 SER HN 2.50 # s 2 16630000.0 e 4122-12 510
HN 9 ASP HB2 3.10 # 3 2955000.0 e 4122-12 490
HA 5 GLN HB2 3.40 # 2 2208000.0 e 4122-12 235
HA 5 GLN HB3 3.10 # 2 4202000.0 e 4122-12 236
HA 5 GLN HG2 2.50 <# s 1 3754000.0 e 4122-12 237
HA 5 GLN HG3 3.30 ># 1 624100.0 e 4122-12 238
HB2 6 SER HN 3.70 <# 2 1400000.0 e 4122-12 68
HB3 6 SER HN 4.40 ># 2 460700.0 e 4122-12 69
6 SER
HN 6 SER HB2 4.40 # 2 486700.0 e 4122-12 430
HN 9 ASP HN 3.70 # 3 938000.0 e 4122-12 508
HN 9 ASP HB2 3.30 # 3 1911000.0 e 4122-12 432
HB2 7 VAL HN 4.10 ># 2 695600.0 e 4122-12 470
HB3 7 VAL HN 3.00 <# 2 4917000.0 e 4122-12 472
7 VAL
HN 7 VAL HA 3.20 # 2 3257000.0 e 4122-12 471
HN 7 VAL HB 2.70 # 2 8511000.0 e 4122-12 478
HN 7 VAL QG2 4.20 # 1M 620100.0 e 4122-12 561
HN 8 ARG HN 3.30 # 2 2566000.0 e 4122-12 201
HN 20 CYSS HB2 3.90 # 5 423300.0 e 4122-12 477
HN 20 CYSS HB3 3.70 # 5 577400.0 e 4122-12 476
HA 7 VAL HB 2.80 # 2 7256000.0 e 4122-12 272
HA 7 VAL QG1 4.00 ># 1M 830300.0 e 4122-12 269
HA 7 VAL QG2 3.50 <# s 1M 5395000.0 e 4122-12 268
HA 9 ASP HN 4.40 # 3 361000.0 e 4122-12 123
HA 10 CYSS HN 3.20 # 3 2263000.0 e 4122-12 413
HA 10 CYSS HB2 3.40 # 3 1717000.0 e 4122-12 274
HA 10 CYSS HB3 3.90 # 3 718600.0 e 4122-12 275
HA 20 CYSS HN 3.80 # 4 372800.0 e 4122-12 451
HA 20 CYSS HB2 2.50 <# s 5 5800000.0 e 4122-12 271
HA 20 CYSS HB3 3.20 ># 5 1508000.0 e 4122-12 273
HB 7 VAL QG1 3.50 # s 1M 4018000.0 e 4122-12 339
HB 7 VAL QG2 3.50 # s 1M 5442000.0 e 4122-12 338
HB 8 ARG HN 4.30 # 2 519000.0 e 4122-12 87
HB 19 ARG HA 4.40 # 5 215900.0 e 4122-12 225
HB 20 CYSS HN 3.30 # 5 1180000.0 e 4122-12 32
HB 20 CYSS HB3 4.70 # 5 136700.0 e 4122-12 323
QG1 8 ARG HN 3.90 <# 5M 2180000.0 e 4122-12 557
QG2 8 ARG HN 4.60 ># 5M 802100.0 e 4122-12 81
QG2 10 CYSS HB2 5.40 # 5M 310800.0 e 4122-12 311
QG2 19 ARG HA 4.60 # 5M 761300.0 e 4122-12 222
8 ARG
HN 8 ARG HA 2.90 # 2 5434000.0 e 4122-12 402
HN 8 ARG QB 3.50 # i 2 6000000.0*2e 4122-12 86
HN 8 ARG QG 4.20 # m 1 781500.0*2e 4122-12 85
HN 9 ASP HN 3.10 # 2 3766000.0 e 4122-12 194
HA 9 ASP HN 3.70 # 2 1253000.0 e 4122-12 124
HA 11 GLN HN 3.60 # 3 1121000.0 e 4122-12 404
HA 11 GLN QB 5.40 # m 3 348050.0*2e 4122-12 502
QB 9 ASP HN 4.90 # m 2 961000.0*2e 4122-12 116
9 ASP
HN 9 ASP HB2 2.90 # 2 6417000.0 e 4122-12 391
HN 9 ASP HB3 3.30 # 2 2804000.0 e 4122-12 387
HN 10 CYSS HN 3.00 # 2 5280000.0 e 4122-12 195
HB2 10 CYSS HN 3.80 # 2 1230000.0 e 4122-12 91
10 CYSS
HN 10 CYSS HB2 2.80 <# 2 7503000.0 e 4122-12 100
HN 10 CYSS HB3 3.40 ># 2 2196000.0 e 4122-12 92
HA 10 CYSS HB2 3.30 # 2 2517000.0 e 4122-12 212
HA 10 CYSS HB3 3.00 # 2 4609000.0 e 4122-12 213
HA 12 GLN HN 4.70 # 3 242600.0 e 4122-12 563
HA 13 TYR HB2 4.10 # 3 556400.0 e 4122-12 210
HA 13 TYR QD 5.10 # r 5 1870000.0*2e 4122-12 363
HB2 11 GLN HN 4.20 # 2 619400.0 e 4122-12 104
HB2 17 PRO HB2 3.00 # 5 2151000.0 e 4122-12 548
HB2 17 PRO HB3 2.80 # 5 3577000.0 e 4122-12 547
HB2 17 PRO HG2 4.20 # 5 292500.0 e 4122-12 549
HB2 25 CYSS QB 4.70 ># m 5 568000.0*2e 4122-12 539
HB3 17 PRO HB2 3.50 # 5 785200.0 e 4122-12 308
HB3 17 PRO HB3 3.00 # 5 2200000.0 e 4122-12 309
HB3 25 CYSS QB 3.80 <# m 5 3161500.0*2e 4122-12 543
11 GLN
HN 11 GLN HA 2.90 # 2 6374000.0 e 4122-12 399
HN 11 GLN QB 3.50 # i 2 5705000.0*2e 4122-12 101
HN 11 GLN HG2 4.10 ># 1 160700.0 e 4122-12 417
HN 11 GLN HG3 2.80 <# 1 1828000.0 e 4122-12 103
HN 12 GLN HN 3.00 # 2 4971000.0 e 4122-12 193
HA 11 GLN QB 4.10 # m 2 4246000.0*2e 4122-12 252
HA 11 GLN HG2 3.10 # 1 904300.0 e 4122-12 253
HA 11 GLN HG3 3.50 # 1 429700.0 e 4122-12 254
HA 12 GLN HN 3.70 # 2 1319000.0 e 4122-12 396
HA 13 TYR HN 5.00 # w 3 84790.0 e 4122-12 568
HA 14 CYSS HN 3.60 # 3 1116000.0 e 4122-12 381
HA 17 PRO HG2 3.10 <# 5 1769000.0 e 4122-12 250
HA 17 PRO HG3 3.90 ># 5 444400.0 e 4122-12 251
QB 11 GLN HG3 3.60 # m 1 2484500.0*2e 4122-12 523
QB 12 GLN HN 4.70 # m 2 1460000.0*2e 4122-12 405
12 GLN
HN 12 GLN HA 3.10 # 2 4305000.0 e 4122-12 397
HN 12 GLN HB2 3.30 # 2 2799000.0 e 4122-12 408
HN 12 GLN HG3 2.90 # 1 1538000.0 e 4122-12 406
HN 13 TYR HN 2.90 # 2 5692000.0 e 4122-12 506
HA 12 GLN HG3 3.60 # 1 398200.0 e 4122-12 504
HA 13 TYR HN 4.10 # 2 755800.0 e 4122-12 140
13 TYR
HN 14 CYSS HN 2.70 # 2 8408000.0 e 4122-12 188
HA 13 TYR HB2 4.10 ># 2 736200.0 e 4122-12 226
HA 13 TYR HB3 3.50 <# 2 1850000.0 e 4122-12 227
HA 13 TYR QD 3.80 # m 1 1580500.0*2e 4122-12 364
HA 14 CYSS HN 5.00 # w 2 133700.0 e 4122-12 380
HB2 13 TYR QD 4.50 # r s 1 6615000.0*2e 4122-12 371
HB2 14 CYSS HN 3.70 # 2 1354000.0 e 4122-12 118
HB3 13 TYR QD 4.50 # r s 1 4914000.0*2e 4122-12 147
HB3 14 CYSS HN 4.10 # 2 733200.0 e 4122-12 127
QD 25 CYSS QB 7.10 # rm 5 300500.0*4e 4122-12 372
14 CYSS
HN 14 CYSS HB2 3.10 <# 2 3634000.0 e 4122-12 389
HN 14 CYSS HB3 3.80 ># 2 1209000.0 e 4122-12 119
HA 14 CYSS HB2 3.60 # 2 1657000.0 e 4122-12 209
HA 14 CYSS HB3 3.30 # 2 2619000.0 e 4122-12 211
HA 15 LEU HN 2.70 # 2 8622000.0 e 4122-12 567
HB2 15 LEU HN 5.00 ># w 2 149500.0 e 4122-12 66
HB2 16 THR HN 5.00 ># w 3 110900.0 e 4122-12 67
HB2 17 PRO HD2 3.70 # 5 638100.0 e 4122-12 282
HB3 15 LEU HN 3.70 <# 2 1452000.0 e 4122-12 63
HB3 16 THR HN 3.20 <# 3 2300000.0 e 4122-12 62
HB3 17 PRO HA 3.20 # 3 2368000.0 e 4122-12 239
HB3 17 PRO HD2 3.70 # 5 570100.0 e 4122-12 283
HB3 27 CYSS HB3 2.70 # 5 4002000.0 e 4122-12 278
15 LEU
HN 15 LEU HA 3.00 # 2 4492000.0 e 4122-12 436
HA 15 LEU QD1 3.70 # 1M 1271000.0 e 4122-12 248
HA 15 LEU QD2 4.00 # 1M 823300.0 e 4122-12 249
16 THR
HN 16 THR HB 3.20 # 2 3420000.0 e 4122-12 437
HB 16 THR QG2 3.50 # s 1M 6386000.0 e 4122-12 259
HB 28 LYS HN 4.10 # 5 334800.0 e 4122-12 51
QG2 17 PRO HD3 5.80 # 5M 188000.0 e 4122-12 266
17 PRO
HA 17 PRO HB2 3.20 # 2 3168000.0 e 4122-12 241
HA 17 PRO HB3 3.10 # 2 3658000.0 e 4122-12 242
HA 18 ASP HN 2.80 # 2 7994000.0 e 4122-12 475
HA 28 LYS HN 3.20 # 4 1023000.0 e 4122-12 444
HB2 17 PRO HD2 3.90 # 1 214300.0 e 4122-12 280
HB2 17 PRO HD3 3.30 # 1 629900.0 e 4122-12 265
HG2 17 PRO HD2 2.50 # s 1 4717000.0 e 4122-12 279
HG2 17 PRO HD3 2.80 # 1 1634000.0 e 4122-12 267
HG3 17 PRO HD2 2.70 # 1 2271000.0 e 4122-12 281
HG3 17 PRO HD3 2.50 # s 1 5300000.0 e 4122-12 264
18 ASP
HN 18 ASP HB2 3.30 # 2 2809000.0 e 4122-12 482
HN 18 ASP HB3 3.10 # 2 3933000.0 e 4122-12 481
HN 19 ARG HN 2.80 # 2 7137000.0 e 4122-12 509
HN 28 LYS HN 3.60 # 4 517000.0 e 4122-12 181
HB2 19 ARG HN 3.70 ># 2 1256000.0 e 4122-12 88
HB2 26 TYR HB2 3.90 # 5 434400.0 e 4122-12 522
HB2 28 LYS HN 3.50 # 5 858500.0 e 4122-12 453
HB2 28 LYS HA 4.00 # 5 347700.0 e 4122-12 231
HB2 28 LYS QG 4.20 <# m 5 1466000.0*2e 4122-12 330
HB3 19 ARG HN 2.80 <# 2 7051000.0 e 4122-12 89
HB3 19 ARG HG3 3.70 # 5 613700.0 e 4122-12 329
HB3 26 TYR HB2 2.90 # 5 2573000.0 e 4122-12 321
HB3 26 TYR HB3 3.20 # 5 1522000.0 e 4122-12 310
HB3 28 LYS QG 6.00 ># m w 5 51150.0*2e 4122-12 328
19 ARG
HN 19 ARG HG2 3.40 ># 1 535300.0 e 4122-12 83
HN 19 ARG HG3 2.50 <# s 1 3357000.0 e 4122-12 84
HN 26 TYR HN 3.20 # 4 1134000.0 e 4122-12 202
HN 26 TYR HB2 2.90 <# 5 2550000.0 e 4122-12 90
HN 26 TYR HB3 3.50 ># 5 836300.0 e 4122-12 99
HA 19 ARG HB2 3.60 # 2 1664000.0 e 4122-12 223
HA 19 ARG HB3 3.70 # 2 1292000.0 e 4122-12 224
HA 20 CYSS HN 3.00 # 2 5249000.0 e 4122-12 445
HB2 19 ARG QD 3.80 # m 1 1691500.0*2e 4122-12 517
HB2 20 CYSS HN 3.30 <# 2 2960000.0 e 4122-12 465
HB2 26 TYR HB2 3.60 # 5 670100.0 e 4122-12 518
HB3 19 ARG QD 3.60 # m 1 3067000.0*2e 4122-12 516
HB3 20 CYSS HN 4.10 ># 2 689100.0 e 4122-12 466
HG2 19 ARG QD 3.60 # m 1 2810500.0*2e 4122-12 315
HG2 19 ARG HE 3.20 # 1 712900.0 e 4122-12 159
HG2 20 CYSS HN 5.00 # 5 94520.0 e 4122-12 30
HG2 21 SER HB2 3.60 # 5 708600.0 e 4122-12 284
HG2 26 TYR HB2 3.00 # 5 2307000.0 e 4122-12 314
HG2 26 TYR HB3 4.30 # 5 245800.0 e 4122-12 301
HG2 26 TYR QD 5.20 <# r 5 1319500.0*2e 4122-12 151
HG3 19 ARG QD 3.60 # m 1 3025500.0*2e 4122-12 316
HG3 19 ARG HE 3.30 # 1 682900.0 e 4122-12 160
HG3 26 TYR HB2 2.50 # s 5 7041000.0 e 4122-12 313
HG3 26 TYR HB3 3.20 # 5 1502000.0 e 4122-12 302
HG3 26 TYR QD 6.00 ># r 5 381750.0*2e 4122-12 152
QD 19 ARG HE 3.50 # m s 1 3464000.0*2e 4122-12 165
HE 21 SER HB2 4.20 # 5 293100.0 e 4122-12 354
20 CYSS
HN 20 CYSS HA 3.40 # 2 2104000.0 e 4122-12 499
HN 20 CYSS HB2 3.30 # 2 2574000.0 e 4122-12 455
HN 20 CYSS HB3 2.90 # 2 6049000.0 e 4122-12 454
HA 20 CYSS HB2 2.90 # 2 5433000.0 e 4122-12 207
HA 20 CYSS HB3 3.30 # 2 2784000.0 e 4122-12 208
HA 21 SER HN 2.60 # 2 11990000.0 e 4122-12 501
HA 26 TYR HN 4.20 # 4 197700.0 e 4122-12 500
21 SER
HN 21 SER HB2 3.60 # 2 1527000.0 e 4122-12 23
HN 21 SER HB3 3.70 # 2 1353000.0 e 4122-12 468
HN 24 THR HN 3.30 # 3 1858000.0 e 4122-12 176
HN 24 THR HB 5.00 # 3 151900.0 e 4122-12 467
HN 26 TYR QD 5.60 # r 5 751500.0*2e 4122-12 205
HN 26 TYR QE 5.70 # r 5 623000.0*2e 4122-12 206
HB2 26 TYR QD 5.90 # r 5 430850.0*2e 4122-12 156
HB2 26 TYR QE 5.20 # r 5 1352000.0*2e 4122-12 167
HB3 26 TYR QD 6.10 # r 5 297850.0*2e 4122-12 157
HB3 26 TYR QE 5.20 # r 5 1582000.0*2e 4122-12 168
22 TYR
HN 22 TYR HA 2.70 # 2 10330000.0 e 4122-12 473
HN 22 TYR HB2 5.00 # w 2 183100.0 e 4122-12 480
HN 22 TYR HB3 4.80 # 2 288300.0 e 4122-12 14
HN 23 GLY HN 3.40 # 2 2323000.0 e 4122-12 174
HA 22 TYR HB2 3.20 # 2 3232000.0 e 4122-12 256
HA 22 TYR HB3 2.80 # 2 7205000.0 e 4122-12 257
HA 22 TYR QD 4.10 # m 1 956500.0*2e 4122-12 565
HA 23 GLY HN 3.00 # 2 4528000.0 e 4122-12 421
HB2 22 TYR QD 4.70 # r 1 2418000.0*2e 4122-12 148
HB3 22 TYR QD 4.80 # r 1 1813500.0*2e 4122-12 149
23 GLY
HN 23 GLY QA 2.90 # 2 5590000.0*2e 4122-12 422
HN 24 THR HN 3.20 # 2 3085000.0 e 4122-12 191
24 THR
HN 24 THR HA 3.60 # 2 1503000.0 e 4122-12 401
HN 24 THR HB 2.90 # 2 5910000.0 e 4122-12 403
HA 24 THR QG2 3.50 # s 1M 3159000.0 e 4122-12 232
HA 25 CYSS HN 2.60 # 2 11370000.0 e 4122-12 439
HA 25 CYSS QB 6.00 # m w 2 151750.0*2e 4122-12 234
HB 24 THR QG2 3.50 # s 1M 8619000.0 e 4122-12 258
HB 26 TYR QE 5.10 # r 5 1873500.0*2e 4122-12 169
QG2 25 CYSS HN 3.70 # 5M 3011000.0 e 4122-12 58
QG2 26 TYR QD 8.00 # r w 5M 64400.0*2e 4122-12 153
QG2 26 TYR QE 6.70 # r 5M 695000.0*2e 4122-12 158
25 CYSS
HN 25 CYSS QB 3.50 # i 2 5865000.0*2e 4122-12 440
HA 25 CYSS QB 4.60 # m 2 1676500.0*2e 4122-12 215
HA 26 TYR HN 3.20 # 2 3172000.0 e 4122-12 498
QB 26 TYR HN 5.10 # m 2 748000.0*2e 4122-12 496
26 TYR
HN 26 TYR HB2 3.00 <# 2 4524000.0 e 4122-12 27
HN 26 TYR HB3 3.90 ># 2 986200.0 e 4122-12 494
HN 26 TYR QD 5.10 # r 1 1028000.0*2e 4122-12 204
HB2 26 TYR QD 4.50 # r s 1 3119500.0*2e 4122-12 154
HB3 26 TYR QD 4.60 # r 1 3001500.0*2e 4122-12 155
HB3 27 CYSS HN 3.80 # 2 1186000.0 e 4122-12 485
27 CYSS
HN 27 CYSS HB3 3.80 # 2 1087000.0 e 4122-12 484
HA 27 CYSS HB2 3.40 # 2 2412000.0 e 4122-12 216
HA 27 CYSS HB3 3.10 # 2 4209000.0 e 4122-12 221
HA 28 LYS HN 3.30 # 2 2487000.0 e 4122-12 497
HB2 28 LYS HN 4.10 ># 2 721400.0 e 4122-12 452
HB3 28 LYS HN 3.10 <# 2 3630000.0 e 4122-12 450
28 LYS
HN 28 LYS HA 3.80 # 2 1161000.0 e 4122-12 443
HN 28 LYS QG 4.20 # m 1 732500.0*2e 4122-12 45
HN 29 THR HN 3.60 # 2 1506000.0 e 4122-12 511
HA 28 LYS QG 4.10 # i 1 443500.0*2e 4122-12 228
HA 29 THR HN 4.50 # 2 398600.0 e 4122-12 56
29 THR
HN 29 THR HA 3.60 # 2 1551000.0 e 4122-12 55
HN 29 THR HB 3.90 # 2 987200.0 e 4122-12 438
HN 30 THR HN 3.90 # 2 938200.0 e 4122-12 183
HA 30 THR HN 3.20 # 2 3513000.0 e 4122-12 423
30 THR
HN 30 THR HB 3.80 # 2 1144000.0 e 4122-12 425
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