BMRB

NMR Restraints Grid

Result table
 (Save to zip file containing files for each block)

image mrblock_id pdb_id bmrb_id cing stage program type subtype subsubtype
554520 2lr1 RC 18340 cing 3-converted-DOCR XPLOR/CNS distance general distance ambi 

 assi 
   (( segid "   B" and resid 131  and name  HA  ))
   (  segid "   B" and resid 131  and name  HG# )
      4.000     1.000     1.000

 assi 
   (( segid "   B" and resid 131  and name  HA  ))
   (( segid "   B" and resid 131  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 131  and name  HA  ))
   (( segid "   B" and resid 132  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (  segid "   B" and resid 131  and name  HB# )
   (( segid "   B" and resid 131  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (  segid "   B" and resid 131  and name  HB# )
   (( segid "   B" and resid 132  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (  segid "   B" and resid 131  and name  HB# )
   (( segid "   B" and resid 133  and name  HN  ))
      4.300     1.100     1.100

 assi 
   (  segid "   B" and resid 131  and name  HG# )
   (( segid "   B" and resid 131  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 131  and name  HN  ))
   (( segid "   B" and resid 132  and name  HN  ))
      3.400     0.800     0.800

 assi 
   (( segid "   B" and resid 132  and name  HA  ))
   (  segid "   B" and resid 132  and name  HB# )
      3.300     1.000     1.000

 assi 
   (( segid "   B" and resid 132  and name  HA  ))
   (( segid "   B" and resid 132  and name  HN  ))
      3.500     1.000     1.000

 assi 
   (( segid "   B" and resid 132  and name  HA  ))
   (( segid "   B" and resid 133  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (  segid "   B" and resid 132  and name  HB# )
   (( segid "   B" and resid 132  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 132  and name  HB# )
   (( segid "   B" and resid 133  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (  segid "   B" and resid 132  and name  HB# )
   (( segid "   B" and resid 134  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (( segid "   B" and resid 132  and name  HN  ))
   (( segid "   B" and resid 133  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 133  and name  HA  ))
   (  segid "   B" and resid 133  and name  HD# )
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 133  and name  HA  ))
   (( segid "   B" and resid 133  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (( segid "   B" and resid 133  and name  HA  ))
   (( segid "   B" and resid 136  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 133  and name  HB# )
   (( segid "   B" and resid 133  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 133  and name  HB# )
   (( segid "   B" and resid 134  and name  HN  ))
      3.400     0.800     0.800

 assi 
   (  segid "   B" and resid 133  and name  HD# )
   (( segid "   B" and resid 133  and name  HN  ))
      4.600     1.100     1.100

 assi 
   (( segid "   B" and resid 133  and name  HN  ))
   (( segid "   B" and resid 135  and name  HN  ))
      4.000     1.000     1.000

 assi 
   (( segid "   B" and resid 134  and name  HN  ))
   (( segid "   B" and resid 136  and name  HN  ))
      4.100     1.000     1.000
 or   
   (( segid "   B" and resid 133  and name  HN  ))
   (( segid "   B" and resid 136  and name  HN  ))

 assi 
   (  segid "   B" and resid 134  and name  HB# )
   (( segid "   B" and resid 136  and name  HN  ))
      3.600     0.900     0.900
 or   
   (  segid "   B" and resid 135  and name  HB# )
   (( segid "   B" and resid 136  and name  HN  ))

 assi 
   (( segid "   B" and resid 134  and name  HA  ))
   (( segid "   B" and resid 134  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (( segid "   B" and resid 134  and name  HA  ))
   (  segid "   B" and resid 137  and name  HB# )
      3.600     1.000     1.000

 assi 
   (( segid "   B" and resid 134  and name  HA  ))
   (  segid "   B" and resid 137  and name  HD# )
      4.100     1.000     1.000

 assi 
   (  segid "   B" and resid 134  and name  HB# )
   (( segid "   B" and resid 134  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 134  and name  HG# )
   (( segid "   B" and resid 134  and name  HN  ))
      4.000     1.000     1.000

 assi 
   (( segid "   B" and resid 134  and name  HN  ))
   (( segid "   B" and resid 135  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (( segid "   B" and resid 134  and name  HN  ))
   (( segid "   B" and resid 136  and name  HN  ))
      3.800     0.900     0.900

 assi 
   (( segid "   B" and resid 134  and name  HN  ))
   (( segid "   B" and resid 137  and name  HN  ))
      4.200     1.000     1.000

 assi 
   (( segid "   B" and resid 135  and name  HA  ))
   (( segid "   B" and resid 135  and name  HN  ))
      3.100     0.800     0.800

 assi 
   (( segid "   B" and resid 135  and name  HA  ))
   (( segid "   B" and resid 136  and name  HN  ))
      3.300     0.800     0.800

 assi 
   (( segid "   B" and resid 135  and name  HA  ))
   (( segid "   B" and resid 137  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (  segid "   B" and resid 135  and name  HB# )
   (( segid "   B" and resid 135  and name  HN  ))
      3.200     0.800     0.800

 assi 
   (  segid "   B" and resid 135  and name  HB# )
   (( segid "   B" and resid 137  and name  HN  ))
      4.100     1.000     1.000

 assi 
   (  segid "   B" and resid 135  and name  HG# )
   (( segid "   B" and resid 135  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 135  and name  HN  ))
   (( segid "   B" and resid 136  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 136  and name  HA  ))
   (  segid "   B" and resid 136  and name  HB# )
      3.300     1.000     1.000

 assi 
   (( segid "   B" and resid 136  and name  HA  ))
   (( segid "   B" and resid 136  and name  HN  ))
      3.300     0.800     0.800

 assi 
   (  segid "   B" and resid 136  and name  HB# )
   (( segid "   B" and resid 136  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (  segid "   B" and resid 136  and name  HB# )
   (( segid "   B" and resid 137  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 136  and name  HN  ))
   (( segid "   B" and resid 137  and name  HN  ))
      3.300     0.800     0.800

 assi 
   (( segid "   B" and resid 139  and name  HA  ))
   (( segid "   B" and resid 140  and name  HN  ))
      3.200     0.900     0.900
 or   
   (( segid "   B" and resid 137  and name  HA  ))
   (( segid "   B" and resid 140  and name  HN  ))

 assi 
   (( segid "   B" and resid 137  and name  HA  ))
   (( segid "   B" and resid 140  and name  HD2 ))
      4.400     1.100     1.100
 or   
   (( segid "   B" and resid 137  and name  HA  ))
   (( segid "   B" and resid 140  and name  HD1 ))

 assi 
   (( segid "   B" and resid 137  and name  HA  ))
   (  segid "   B" and resid 137  and name  HD# )
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 137  and name  HA  ))
   (( segid "   B" and resid 137  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (  segid "   B" and resid 137  and name  HB# )
   (( segid "   B" and resid 137  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 137  and name  HD# )
   (( segid "   B" and resid 140  and name  HD1 ))
      4.500     1.100     1.100
 or   
   (  segid "   B" and resid 137  and name  HD# )
   (( segid "   B" and resid 140  and name  HD2 ))

 assi 
   (  segid "   B" and resid 137  and name  HD# )
   (( segid "   B" and resid 137  and name  HN  ))
      4.200     1.100     1.100

 assi 
   (  segid "   B" and resid 137  and name  HD# )
   (( segid "   B" and resid 138  and name  HN  ))
      4.500     1.200     1.200

 assi 
   (( segid "   B" and resid 137  and name  HN  ))
   (( segid "   B" and resid 138  and name  HN  ))
      3.200     0.800     0.800

 assi 
   (( segid "   B" and resid 138  and name  HA  ))
   (  segid "   B" and resid 138  and name  HD# )
      3.600     0.900     0.900

 assi 
   (( segid "   B" and resid 138  and name  HA  ))
   (( segid "   B" and resid 138  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (  segid "   B" and resid 138  and name  HB# )
   (( segid "   B" and resid 138  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 138  and name  HG# )
   (( segid "   B" and resid 138  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 139  and name  HA  ))
   (  segid "   B" and resid 142  and name  HB# )
      4.400     1.100     1.100

 assi 
   (( segid "   B" and resid 139  and name  HA  ))
   (( segid "   B" and resid 142  and name  HN  ))
      4.000     1.000     1.000

 assi 
   (( segid "   B" and resid 139  and name  HA  ))
   (  segid "   B" and resid 139  and name  HD# )
      3.600     0.900     0.900

 assi 
   (( segid "   B" and resid 139  and name  HA  ))
   (( segid "   B" and resid 139  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (  segid "   B" and resid 139  and name  HB# )
   (  segid "   B" and resid 140  and name  HB# )
      3.500     0.900     0.900

 assi 
   (  segid "   B" and resid 139  and name  HB# )
   (( segid "   B" and resid 140  and name  HN  ))
      4.000     1.000     1.000

 assi 
   (  segid "   B" and resid 139  and name  HB# )
   (( segid "   B" and resid 142  and name  HN  ))
      4.600     1.100     1.100

 assi 
   (  segid "   B" and resid 139  and name  HB# )
   (( segid "   B" and resid 139  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (( segid "   B" and resid 139  and name  HN  ))
   (( segid "   B" and resid 140  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 140  and name  HA  ))
   (( segid "   B" and resid 140  and name  HB2 ))
      3.700     1.000     1.000

 assi 
   (( segid "   B" and resid 140  and name  HA  ))
   (( segid "   B" and resid 140  and name  HD2 ))
      3.700     0.900     0.900
 or   
   (( segid "   B" and resid 140  and name  HA  ))
   (( segid "   B" and resid 140  and name  HD1 ))

 assi 
   (( segid "   B" and resid 140  and name  HA  ))
   (( segid "   B" and resid 140  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (  segid "   B" and resid 140  and name  HB# )
   (( segid "   B" and resid 140  and name  HD1 ))
      3.400     0.900     0.900
 or   
   (  segid "   B" and resid 140  and name  HB# )
   (( segid "   B" and resid 140  and name  HD2 ))

 assi 
   (  segid "   B" and resid 140  and name  HB# )
   (( segid "   B" and resid 140  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 140  and name  HB# )
   (( segid "   B" and resid 141  and name  HE  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 140  and name  HB# )
   (( segid "   B" and resid 141  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (  segid "   B" and resid 140  and name  HB# )
   (( segid "   B" and resid 142  and name  HN  ))
      4.900     1.200     1.200

 assi 
   (  segid "   B" and resid 140  and name  HB# )
   (  segid "   B" and resid 143  and name  HB# )
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 140  and name  HN  ))
   (( segid "   B" and resid 141  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 140  and name  HN  ))
   (( segid "   B" and resid 142  and name  HN  ))
      4.200     1.000     1.000

 assi 
   (( segid "   B" and resid 141  and name  HA  ))
   (  segid "   B" and resid 141  and name  HD# )
      4.100     1.000     1.000

 assi 
   (( segid "   B" and resid 141  and name  HA  ))
   (( segid "   B" and resid 141  and name  HN  ))
      3.200     0.800     0.800

 assi 
   (( segid "   B" and resid 141  and name  HA  ))
   (( segid "   B" and resid 142  and name  HA  ))
      4.300     1.100     1.100

 assi 
   (( segid "   B" and resid 141  and name  HA  ))
   (( segid "   B" and resid 142  and name  HN  ))
      3.300     0.800     0.800

 assi 
   (( segid "   B" and resid 141  and name  HA  ))
   (  segid "   B" and resid 144  and name  HB# )
      4.400     1.100     1.100

 assi 
   (  segid "   B" and resid 141  and name  HB# )
   (( segid "   B" and resid 141  and name  HE  ))
      4.200     1.100     1.100

 assi 
   (  segid "   B" and resid 141  and name  HB# )
   (( segid "   B" and resid 141  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 141  and name  HB# )
   (( segid "   B" and resid 142  and name  HN  ))
      4.100     1.200     1.200

 assi 
   (  segid "   B" and resid 141  and name  HG# )
   (( segid "   B" and resid 141  and name  HN  ))
      4.100     1.000     1.000

 assi 
   (  segid "   B" and resid 141  and name  HG# )
   (( segid "   B" and resid 142  and name  HN  ))
      4.200     1.000     1.000

 assi 
   (( segid "   B" and resid 141  and name  HN  ))
   (( segid "   B" and resid 144  and name  HN  ))
      4.300     1.100     1.100

 assi 
   (( segid "   B" and resid 142  and name  HA  ))
   (( segid "   B" and resid 145  and name  HN  ))
      4.100     1.100     1.100
 or   
   (( segid "   B" and resid 142  and name  HA  ))
   (( segid "   B" and resid 144  and name  HN  ))

 assi 
   (( segid "   B" and resid 142  and name  HA  ))
   (  segid "   B" and resid 142  and name  HB# )
      4.100     1.700     1.700

 assi 
   (( segid "   B" and resid 142  and name  HA  ))
   (( segid "   B" and resid 142  and name  HN  ))
      3.200     0.800     0.800

 assi 
   (( segid "   B" and resid 142  and name  HA  ))
   (( segid "   B" and resid 143  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (  segid "   B" and resid 142  and name  HB# )
   (( segid "   B" and resid 144  and name  HN  ))
      4.800     1.200     1.200
 or   
   (  segid "   B" and resid 142  and name  HB# )
   (( segid "   B" and resid 145  and name  HN  ))

 assi 
   (  segid "   B" and resid 142  and name  HB# )
   (( segid "   B" and resid 142  and name  HN  ))
      3.500     1.000     1.000

 assi 
   (  segid "   B" and resid 142  and name  HB# )
   (( segid "   B" and resid 143  and name  HN  ))
      4.000     1.000     1.000

 assi 
   (  segid "   B" and resid 142  and name  HD# )
   (( segid "   B" and resid 142  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 142  and name  HN  ))
   (( segid "   B" and resid 143  and name  HN  ))
      3.300     0.800     0.800

 assi 
   (( segid "   B" and resid 142  and name  HN  ))
   (( segid "   B" and resid 145  and name  HN  ))
      4.700     1.200     1.200

 assi 
   (( segid "   B" and resid 143  and name  HA  ))
   (( segid "   B" and resid 145  and name  HN  ))
      3.300     0.900     0.900
 or   
   (( segid "   B" and resid 143  and name  HA  ))
   (( segid "   B" and resid 144  and name  HN  ))

 assi 
   (( segid "   B" and resid 143  and name  HA  ))
   (  segid "   B" and resid 143  and name  HB# )
      3.700     1.000     1.000

 assi 
   (( segid "   B" and resid 143  and name  HA  ))
   (  segid "   B" and resid 143  and name  HD# )
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 143  and name  HA  ))
   (( segid "   B" and resid 143  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (  segid "   B" and resid 143  and name  HB# )
   (( segid "   B" and resid 145  and name  HN  ))
      3.900     1.000     1.000
 or   
   (  segid "   B" and resid 143  and name  HB# )
   (( segid "   B" and resid 144  and name  HN  ))

 assi 
   (  segid "   B" and resid 143  and name  HB# )
   (( segid "   B" and resid 143  and name  HN  ))
      3.600     1.200     1.200

 assi 
   (  segid "   B" and resid 143  and name  HD# )
   (( segid "   B" and resid 143  and name  HN  ))
      4.200     1.100     1.100

 assi 
   (  segid "   B" and resid 143  and name  HD# )
   (( segid "   B" and resid 144  and name  HN  ))
      4.400     1.100     1.100

 assi 
   (( segid "   B" and resid 143  and name  HN  ))
   (( segid "   B" and resid 144  and name  HN  ))
      3.500     0.900     0.900

 assi 
   (( segid "   B" and resid 144  and name  HA  ))
   (  segid "   B" and resid 144  and name  HB# )
      3.500     1.100     1.100

 assi 
   (( segid "   B" and resid 144  and name  HA  ))
   (( segid "   B" and resid 144  and name  HN  ))
      3.200     0.800     0.800

 assi 
   (( segid "   B" and resid 144  and name  HA  ))
   (( segid "   B" and resid 145  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (( segid "   B" and resid 144  and name  HA  ))
   (( segid "   B" and resid 147  and name  HN  ))
      4.800     1.200     1.200

 assi 
   (  segid "   B" and resid 144  and name  HB# )
   (( segid "   B" and resid 144  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 144  and name  HB# )
   (( segid "   B" and resid 145  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (( segid "   B" and resid 145  and name  HA  ))
   (  segid "   B" and resid 145  and name  HG# )
      4.200     1.100     1.100

 assi 
   (( segid "   B" and resid 145  and name  HA  ))
   (( segid "   B" and resid 145  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (( segid "   B" and resid 145  and name  HA  ))
   (  segid "   B" and resid 148  and name  HG# )
      4.800     1.200     1.200

 assi 
   (( segid "   B" and resid 145  and name  HA  ))
   (( segid "   B" and resid 148  and name  HN  ))
      4.700     1.200     1.200

 assi 
   (  segid "   B" and resid 145  and name  HB# )
   (( segid "   B" and resid 145  and name  HN  ))
      3.600     1.000     1.000

 assi 
   (  segid "   B" and resid 145  and name  HE2#)
   (  segid "   B" and resid 145  and name  HG# )
      3.900     1.000     1.000

 assi 
   (  segid "   B" and resid 145  and name  HG# )
   (( segid "   B" and resid 145  and name  HN  ))
      4.100     1.100     1.100

 assi 
   (( segid "   B" and resid 145  and name  HN  ))
   (( segid "   B" and resid 147  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (( segid "   B" and resid 146  and name  HA  ))
   (( segid "   B" and resid 146  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 146  and name  HB# )
   (( segid "   B" and resid 146  and name  HE  ))
      4.100     1.100     1.100

 assi 
   (  segid "   B" and resid 146  and name  HB# )
   (( segid "   B" and resid 146  and name  HN  ))
      3.600     0.900     0.900

 assi 
   (  segid "   B" and resid 146  and name  HG# )
   (( segid "   B" and resid 146  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 146  and name  HN  ))
   (( segid "   B" and resid 148  and name  HN  ))
      4.900     1.200     1.200

 assi 
   (  segid "   B" and resid 147  and name  HB# )
   (( segid "   B" and resid 147  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 147  and name  HB# )
   (( segid "   B" and resid 148  and name  HN  ))
      4.300     1.100     1.100

 assi 
   (  segid "   B" and resid 147  and name  HG# )
   (( segid "   B" and resid 148  and name  HN  ))
      4.300     1.100     1.100

 assi 
   (( segid "   B" and resid 147  and name  HN  ))
   (( segid "   B" and resid 148  and name  HN  ))
      3.800     1.000     1.000

 assi 
   (( segid "   B" and resid 148  and name  HA  ))
   (( segid "   B" and resid 148  and name  HN  ))
      3.200     0.900     0.900

 assi 
   (( segid "   B" and resid 148  and name  HA  ))
   (( segid "   B" and resid 149  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 148  and name  HB# )
   (( segid "   B" and resid 148  and name  HN  ))
      3.800     1.000     1.000

 assi 
   (  segid "   B" and resid 148  and name  HB# )
   (( segid "   B" and resid 149  and name  HN  ))
      4.500     1.200     1.200

 assi 
   (  segid "   B" and resid 148  and name  HE2#)
   (  segid "   B" and resid 148  and name  HG# )
      4.600     1.700     1.700

 assi 
   (  segid "   B" and resid 148  and name  HG# )
   (( segid "   B" and resid 148  and name  HN  ))
      3.900     1.000     1.000

 assi 
   (( segid "   B" and resid 148  and name  HN  ))
   (( segid "   B" and resid 150  and name  HN  ))
      3.300     0.800     0.800

 assi 
   (( segid "   B" and resid 149  and name  HA  ))
   (( segid "   B" and resid 149  and name  HN  ))
      3.400     0.900     0.900

 assi 
   (  segid "   B" and resid 149  and name  HB# )
   (( segid "   B" and resid 149  and name  HN  ))
      4.000     1.000     1.000

 assi 
   (  segid "   B" and resid 149  and name  HB# )
   (( segid "   B" and resid 150  and name  HN  ))
      4.500     1.100     1.100

 assi 
   (  segid "   B" and resid 149  and name  HG# )
   (( segid "   B" and resid 149  and name  HN  ))
      4.500     1.200     1.200

 assi 
   (  segid "   B" and resid 149  and name  HG# )
   (( segid "   B" and resid 150  and name  HN  ))
      4.900     1.200     1.200

 assi 
   (( segid "   B" and resid 150  and name  HA  ))
   (  segid "   B" and resid 150  and name  HB# )
      3.600     1.300     1.300

 assi 
   (( segid "   B" and resid 150  and name  HA  ))
   (( segid "   B" and resid 150  and name  HN  ))
      3.300     0.900     0.900

 assi 
   (  segid "   B" and resid 150  and name  HB# )
   (( segid "   B" and resid 150  and name  HN  ))
      3.700     1.000     1.000

Please acknowledge these references in publications where the data from this site have been utilized.

Contact our support address for help, if required. Sunday, July 12, 2026, 1:06:03 PM Coordinated Universal Time