*HEADER    EXOCYTOSIS                              21-APR-15   2N1T              
*TITLE     DYNAMIC BINDING MODE OF A SYNAPTOTAGMIN-1-SNARE COMPLEX IN SOLUTION   
*COMPND    MOL_ID: 1;                                                            
*COMPND   2 MOLECULE: VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;                     
*COMPND   3 CHAIN: A;                                                            
*COMPND   4 FRAGMENT: UNP RESIDUES 25-93;                                        
*COMPND   5 SYNONYM: VAMP-2, SYNAPTOBREVIN-2;                                    
*COMPND   6 ENGINEERED: YES;                                                     
*COMPND   7 MOL_ID: 2;                                                           
*COMPND   8 MOLECULE: SYNTAXIN-1A;                                               
*COMPND   9 CHAIN: B;                                                            
*COMPND  10 FRAGMENT: UNP RESIDUES 188-259;                                      
*COMPND  11 SYNONYM: NEURON-SPECIFIC ANTIGEN HPC-1, SYNAPTOTAGMIN-ASSOCIATED 35  
*COMPND  12 KDA PROTEIN, P35A;                                                   
*COMPND  13 ENGINEERED: YES;                                                     
*COMPND  14 MOL_ID: 3;                                                           
*COMPND  15 MOLECULE: SYNAPTOSOMAL-ASSOCIATED PROTEIN 25;                        
*COMPND  16 CHAIN: C;                                                            
*COMPND  17 FRAGMENT: N-TERMINAL DOMAIN (UNP RESIDUES 7-83);                     
*COMPND  18 SYNONYM: SNAP-25, SNAP-25A, SUPER PROTEIN, SUP, SYNAPTOSOMAL-        
*COMPND  19 ASSOCIATED 25 KDA PROTEIN;                                           
*COMPND  20 ENGINEERED: YES;                                                     
*COMPND  21 MOL_ID: 4;                                                           
*COMPND  22 MOLECULE: SYNAPTOSOMAL-ASSOCIATED PROTEIN 25;                        
*COMPND  23 CHAIN: D;                                                            
*COMPND  24 FRAGMENT: C-TERMINAL DOMAIN (UNP RESIDUES 131-204);                  
*COMPND  25 SYNONYM: SNAP-25, SNAP-25A, SUPER PROTEIN, SUP, SYNAPTOSOMAL-        
*COMPND  26 ASSOCIATED 25 KDA PROTEIN;                                           
*COMPND  27 ENGINEERED: YES;                                                     
*COMPND  28 MOL_ID: 5;                                                           
*COMPND  29 MOLECULE: SYNAPTOTAGMIN-1;                                           
*COMPND  30 CHAIN: E;                                                            
*COMPND  31 FRAGMENT: C2B DOMAIN (UNP RESIDUES 272-419);                         
*COMPND  32 SYNONYM: SYNAPTOTAGMIN I, SYTI, P65;                                 
*COMPND  33 ENGINEERED: YES                                                      
*SOURCE    MOL_ID: 1;                                                            
*SOURCE   2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS;                              
*SOURCE   3 ORGANISM_COMMON: BROWN RAT,RAT,RATS;                                 
*SOURCE   4 ORGANISM_TAXID: 10116;                                               
*SOURCE   5 GENE: SYB2, VAMP2;                                                   
*SOURCE   6 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE   7 EXPRESSION_SYSTEM_TAXID: 562;                                        
*SOURCE   8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE   9 EXPRESSION_SYSTEM_PLASMID: PGEX-KT;                                  
*SOURCE  10 MOL_ID: 2;                                                           
*SOURCE  11 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS;                              
*SOURCE  12 ORGANISM_COMMON: BROWN RAT,RAT,RATS;                                 
*SOURCE  13 ORGANISM_TAXID: 10116;                                               
*SOURCE  14 GENE: SAP, STX1A;                                                    
*SOURCE  15 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE  16 EXPRESSION_SYSTEM_TAXID: 562;                                        
*SOURCE  17 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE  18 EXPRESSION_SYSTEM_PLASMID: PGEX-KT;                                  
*SOURCE  19 MOL_ID: 3;                                                           
*SOURCE  20 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE  21 ORGANISM_COMMON: HUMAN;                                              
*SOURCE  22 ORGANISM_TAXID: 9606;                                                
*SOURCE  23 GENE: SNAP, SNAP25, SNAP-25A;                                        
*SOURCE  24 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE  25 EXPRESSION_SYSTEM_TAXID: 562;                                        
*SOURCE  26 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE  27 EXPRESSION_SYSTEM_PLASMID: PGEX-KT;                                  
*SOURCE  28 MOL_ID: 4;                                                           
*SOURCE  29 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE  30 ORGANISM_COMMON: HUMAN;                                              
*SOURCE  31 ORGANISM_TAXID: 9606;                                                
*SOURCE  32 GENE: SNAP, SNAP25, SNAP-25A;                                        
*SOURCE  33 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE  34 EXPRESSION_SYSTEM_TAXID: 562;                                        
*SOURCE  35 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE  36 EXPRESSION_SYSTEM_PLASMID: PGEX-KT;                                  
*SOURCE  37 MOL_ID: 5;                                                           
*SOURCE  38 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE  39 ORGANISM_COMMON: HUMAN;                                              
*SOURCE  40 ORGANISM_TAXID: 9606;                                                
*SOURCE  41 GENE: SVP65, SYT, SYT1;                                              
*SOURCE  42 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE  43 EXPRESSION_SYSTEM_TAXID: 562;                                        
*SOURCE  44 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE  45 EXPRESSION_SYSTEM_PLASMID: PGEX-KT                                   
*KEYWDS    SYNAPTOTAGMIN-1, C2B DOMAIN, SYNTAXIN-1A, SYNAPTOBREVIN-2, SNAP-25,   
*KEYWDS   2 SNAP-25A, SNARE COMPLEX, EXOCYTOSIS                                  
*EXPDTA    SOLUTION NMR                                                          
*NUMMDL    5                                                                     
*AUTHOR    K.BREWER, T.BACAJ, A.CAVALLI, C.CAMILLONI, J.SWARBRICK, J.LIU,        
*AUTHOR   2 A.ZHOU, P.ZHOU, N.BARLOW, J.XU, A.SEVEN, E.PRINSLOW, R.VOLETI,       
*AUTHOR   3 D.HAUSSINGER, A.BONVIN, D.TOMCHICK, M.VENDRUSCOLO, B.GRAHAM,         
*AUTHOR   4 T.SUDHOF, J.RIZO                                                     
*REVDAT   1   03-JUN-15 2N1T    0                                                


