*HEADER    APOPTOSIS                               25-SEP-13   2MEJ              
*TITLE     SOLUTION STRUCTURE OF THE COMPLEX BETWEEN BCL-XL AND THE P53 CORE     
*TITLE    2 DOMAIN DETERMINED WITH PRE RESTRAINTS                                
*COMPND    MOL_ID: 1;                                                            
*COMPND   2 MOLECULE: BCL-2-LIKE PROTEIN 1;                                      
*COMPND   3 CHAIN: A;                                                            
*COMPND   4 FRAGMENT: UNP RESIDUES 1-198;                                        
*COMPND   5 SYNONYM: BCL2-L-1, APOPTOSIS REGULATOR BCL-X;                        
*COMPND   6 ENGINEERED: YES;                                                     
*COMPND   7 MOL_ID: 2;                                                           
*COMPND   8 MOLECULE: CELLULAR TUMOR ANTIGEN P53;                                
*COMPND   9 CHAIN: B;                                                            
*COMPND  10 FRAGMENT: UNP RESIDUES 96-312;                                       
*COMPND  11 SYNONYM: ANTIGEN NY-CO-13, PHOSPHOPROTEIN P53, TUMOR SUPPRESSOR P53; 
*COMPND  12 ENGINEERED: YES                                                      
*SOURCE    MOL_ID: 1;                                                            
*SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
*SOURCE   4 ORGANISM_TAXID: 9606;                                                
*SOURCE   5 GENE: BCL2L1, BCL2L, BCLX;                                           
*SOURCE   6 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE   7 EXPRESSION_SYSTEM_TAXID: 469008;                                     
*SOURCE   8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3);                                 
*SOURCE   9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE  10 EXPRESSION_SYSTEM_PLASMID: PET28;                                    
*SOURCE  11 MOL_ID: 2;                                                           
*SOURCE  12 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE  13 ORGANISM_COMMON: HUMAN;                                              
*SOURCE  14 ORGANISM_TAXID: 9606;                                                
*SOURCE  15 GENE: TP53, P53;                                                     
*SOURCE  16 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE  17 EXPRESSION_SYSTEM_TAXID: 469008;                                     
*SOURCE  18 EXPRESSION_SYSTEM_STRAIN: BL21(DE3);                                 
*SOURCE  19 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE  20 EXPRESSION_SYSTEM_PLASMID: PET28                                     
*KEYWDS    BCL-XL, P53, APOPTOSIS, BCL-2 FAMILY, CYTOPLASMIC P53, SELECTIVE      
*KEYWDS   2 LABELING                                                             
*EXPDTA    SOLUTION NMR                                                          
*NUMMDL    20                                                                    
*AUTHOR    A.VIACAVA FOLLIS, C.R.GRACE, R.W.KRIWACKI                             
*REVDAT   1   30-APR-14 2MEJ    0                                                



