*HEADER    PROTEIN BINDING                         07-DEC-07   2JY7              
*TITLE     NMR STRUCTURE OF THE UBIQUITIN ASSOCIATED (UBA) DOMAIN OF             
*TITLE    2 P62 (SQSTM1). RDC REFINED                                            
*COMPND    MOL_ID: 1;                                                            
*COMPND   2 MOLECULE: UBIQUITIN-BINDING PROTEIN P62;                             
*COMPND   3 CHAIN: A;                                                            
*COMPND   4 FRAGMENT: UBA DOMAIN;                                                
*COMPND   5 SYNONYM: SEQUESTOSOME-1, PHOSPHOTYROSINE-INDEPENDENT                 
*COMPND   6 LIGAND FOR THE LCK SH2 DOMAIN OF 62 KDA, EBI3-ASSOCIATED             
*COMPND   7 PROTEIN OF 60 KDA, P60, EBIAP;                                       
*COMPND   8 ENGINEERED: YES                                                      
*SOURCE    MOL_ID: 1;                                                            
*SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
*SOURCE   4 GENE: SQSTM1, ORCA, OSIL;                                            
*SOURCE   5 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE   6 EXPRESSION_SYSTEM_STRAIN: BL21;                                      
*SOURCE   7 EXPRESSION_SYSTEM_VARIANT: (DE3);                                    
*SOURCE   8 EXPRESSION_SYSTEM_VECTOR_TYPE: VECTOR;                               
*SOURCE   9 EXPRESSION_SYSTEM_VECTOR: PGEX-4T-1                                  
*KEYWDS    UBIQUITIN BINDING, UBIQUITIN ASSOCIATED DOMAIN, HELICAL               
*KEYWDS   2 BUNDLE, THREE HELICES, ALTERNATIVE SPLICING, APOPTOSIS,              
*KEYWDS   3 CYTOPLASM, DIFFERENTIATION, DISEASE MUTATION, ENDOSOME,              
*KEYWDS   4 IMMUNE RESPONSE, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN,             
*KEYWDS   5 POLYMORPHISM, ZINC, ZINC-FINGER, PROTEIN BINDING                     
*EXPDTA    NMR, 30 STRUCTURES                                                    
*AUTHOR    J.E.LONG, R.LAYFIELD, M.S.SEARLE                                      
*REVDAT   1   18-DEC-07 2JY7    0                                                


