*HEADER    SIGNALING PROTEIN                       14-MAY-03   1PB5              
*TITLE     NMR STRUCTURE OF A PROTOTYPE LNR MODULE FROM HUMAN NOTCH1             
*COMPND    MOL_ID: 1;                                                            
*COMPND   2 MOLECULE: NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1;                  
*COMPND   3 CHAIN: A;                                                            
*COMPND   4 FRAGMENT: FIRST LNR MODULE;                                          
*COMPND   5 SYNONYM: NOTCH 1, HN1, TRANSLOCATION-ASSOCIATED NOTCH                
*COMPND   6 PROTEIN TAN-1;                                                       
*COMPND   7 ENGINEERED: YES                                                      
*SOURCE    MOL_ID: 1;                                                            
*SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
*SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
*SOURCE   4 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
*SOURCE   5 EXPRESSION_SYSTEM_COMMON: BACTERIA;                                  
*SOURCE   6 EXPRESSION_SYSTEM_STRAIN: BL21DE3PLYSS;                              
*SOURCE   7 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
*SOURCE   8 EXPRESSION_SYSTEM_PLASMID: PMM                                       
*KEYWDS    NOTCH SIGNALING, LIN12/NOTCH REPEAT, CALCIUM-BINDING DOMAIN,          
*KEYWDS   2 PROTEIN MODULE, DISULFIDE BOND                                       
*EXPDTA    NMR, 16 STRUCTURES                                                    
*AUTHOR    D.VARDAR, C.L.NORTH, C.SANCHEZ-IRIZARRY, J.C.ASTER,                   
*AUTHOR   2 S.C.BLACKLOW                                                         
*REVDAT   1   17-JUN-03 1PB5    0                                                


